Review



il-22 cytokine  (PeproTech)


Bioz Verified Symbol PeproTech is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 90

    Structured Review

    PeproTech il-22 cytokine
    Il 22 Cytokine, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/il-22+cytokine/il+22+cytokine/pm40358149-84-5-7
    Average 90 stars, based on 1 article reviews
    il-22 cytokine - by Bioz Stars, 2026-10
    90/100 stars

    Images

    Related Articles

    Recombinant:

    Article Title: C5a peptidase (ScpA) activity towards human type II and type III interferons.
    Article Snippet: IL-37, IL-22, IL-6, IL-8, IL10, IL-17A, IL-17E, IL-1α, IP-10, ENA-78, TNF-α, MIG, IFNβ, IFNω, IFNγ, IFNλ1, IFNλ2 were purchased from Peprotech.

    Article Title: Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis.
    Article Snippet: Circular RNA (circRNA) has been confirmed to participate in psoriasis process, but the role of circ_0024028 in psoriasis development is still unclear.. Interleukin 22 (IL-22)-induced keratinocytes (HaCaT) were used to construct psoriasis cell models in vitro.. The expression of circ_0024028, microRNA (miR)-486-3p and AKT serine/threonine kinase 3 (AKT3) was analyzed by quantitative real-time PCR.

    Article Title: Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
    Article Snippet: KCs and HaCaT cells were stimulated with a mix of proinflammatory cytokines namely IL-1α (Biomart), IL-6 (Peprotech), TNF-α (Prospec), IL-17 (Biomart), IL-22 (Peprotech) and IFN-γ (Peprotech), each at 50 ng/ml, for 24 h. Conditioned media were concentrated 10 times by using centrifugal concentrator with 10,000 MW cutoff (Vivaspin, Sartorius).

    Article Title: The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration
    Article Snippet: The concentration of IL-22 (PeproTech, cat: 200-22), IL-17A (PeproTech, cat: 200-17), TNF-α (PeproTech, cat: 300-01A), IL-1a (PeproTech, cat: 200-01A), and oncostatin M (PeproTech, cat: 300-10H) used in this study was 10 ng/mL.

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation.
    Article Snippet: The M6 cocktail contains IL-4 (10 ng/ml, Peprotech, Cat# 200--04), IL-17A (10 ng/ml, Peprotech, Cat# 200--17), IL-22 (10 ng/ml, Peprotech, Cat# 200--22), oncostatin M (10 ng/ml, Peprotech, Cat# 300--10), IL-1α (10 ng/ml, Peprotech, Cat# 200--01 A), and TNF-α (10 ng/ml, Peprotech, Cat# 300--01 A).

    Article Title: Platelet-Derived Soluble CD40L and Its Impact on Immune Modulation and Anti-IL6R Antibody Treatment Outcome in Rheumatoid Arthritis.
    Article Snippet: IFNγ, TNF (BD Biosciences), IL-17, VEGF, IL-22 (Peprotech), IL-6, sIL-6R, IL-10 (Immunotools), sCD62P (R&D, Minneapolis, MN, USA) PF-4, sCD40L, PDGF-BB (Peprotech), and latent TGFβ (Mabtech, Nacka Strand, Sweden) levels were determined using specific ELISA kits according to manufacturers’ instruction.

    Article Title: CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
    Article Snippet: Isolated LSECs were subsequently cultured on collagen-coated plates using IMDM medium (10% FBS) for 5 days before IL-22 (PeproTech) stimulation (50 ng/ml).

    Article Title: Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing
    Article Snippet: For the subsequent inflammatory model, additional cytokines including recombinant human interleukin (IL)-17A, tumor necrosis factor (TNF)-α and IL-22 (at a concentration of 50 ng/mL each) (catalog # 200-17, 300-01A, or 200-22, PeproTech, US) were added.

    Concentration Assay:

    Article Title: C5a peptidase (ScpA) activity towards human type II and type III interferons.
    Article Snippet: IL-37, IL-22, IL-6, IL-8, IL10, IL-17A, IL-17E, IL-1α, IP-10, ENA-78, TNF-α, MIG, IFNβ, IFNω, IFNγ, IFNλ1, IFNλ2 were purchased from Peprotech.

    Article Title: Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis.
    Article Snippet: Circular RNA (circRNA) has been confirmed to participate in psoriasis process, but the role of circ_0024028 in psoriasis development is still unclear.. Interleukin 22 (IL-22)-induced keratinocytes (HaCaT) were used to construct psoriasis cell models in vitro.. The expression of circ_0024028, microRNA (miR)-486-3p and AKT serine/threonine kinase 3 (AKT3) was analyzed by quantitative real-time PCR.

    Article Title: Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
    Article Snippet: KCs and HaCaT cells were stimulated with a mix of proinflammatory cytokines namely IL-1α (Biomart), IL-6 (Peprotech), TNF-α (Prospec), IL-17 (Biomart), IL-22 (Peprotech) and IFN-γ (Peprotech), each at 50 ng/ml, for 24 h. Conditioned media were concentrated 10 times by using centrifugal concentrator with 10,000 MW cutoff (Vivaspin, Sartorius).

    Article Title: The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration
    Article Snippet: The concentration of IL-22 (PeproTech, cat: 200-22), IL-17A (PeproTech, cat: 200-17), TNF-α (PeproTech, cat: 300-01A), IL-1a (PeproTech, cat: 200-01A), and oncostatin M (PeproTech, cat: 300-10H) used in this study was 10 ng/mL.

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation.
    Article Snippet: The M6 cocktail contains IL-4 (10 ng/ml, Peprotech, Cat# 200--04), IL-17A (10 ng/ml, Peprotech, Cat# 200--17), IL-22 (10 ng/ml, Peprotech, Cat# 200--22), oncostatin M (10 ng/ml, Peprotech, Cat# 300--10), IL-1α (10 ng/ml, Peprotech, Cat# 200--01 A), and TNF-α (10 ng/ml, Peprotech, Cat# 300--01 A).

    Article Title: Platelet-Derived Soluble CD40L and Its Impact on Immune Modulation and Anti-IL6R Antibody Treatment Outcome in Rheumatoid Arthritis.
    Article Snippet: IFNγ, TNF (BD Biosciences), IL-17, VEGF, IL-22 (Peprotech), IL-6, sIL-6R, IL-10 (Immunotools), sCD62P (R&D, Minneapolis, MN, USA) PF-4, sCD40L, PDGF-BB (Peprotech), and latent TGFβ (Mabtech, Nacka Strand, Sweden) levels were determined using specific ELISA kits according to manufacturers’ instruction.

    Article Title: CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
    Article Snippet: Isolated LSECs were subsequently cultured on collagen-coated plates using IMDM medium (10% FBS) for 5 days before IL-22 (PeproTech) stimulation (50 ng/ml).

    Article Title: Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing
    Article Snippet: For the subsequent inflammatory model, additional cytokines including recombinant human interleukin (IL)-17A, tumor necrosis factor (TNF)-α and IL-22 (at a concentration of 50 ng/mL each) (catalog # 200-17, 300-01A, or 200-22, PeproTech, US) were added.

    Isolation:

    Article Title: C5a peptidase (ScpA) activity towards human type II and type III interferons.
    Article Snippet: IL-37, IL-22, IL-6, IL-8, IL10, IL-17A, IL-17E, IL-1α, IP-10, ENA-78, TNF-α, MIG, IFNβ, IFNω, IFNγ, IFNλ1, IFNλ2 were purchased from Peprotech.

    Article Title: Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis.
    Article Snippet: Circular RNA (circRNA) has been confirmed to participate in psoriasis process, but the role of circ_0024028 in psoriasis development is still unclear.. Interleukin 22 (IL-22)-induced keratinocytes (HaCaT) were used to construct psoriasis cell models in vitro.. The expression of circ_0024028, microRNA (miR)-486-3p and AKT serine/threonine kinase 3 (AKT3) was analyzed by quantitative real-time PCR.

    Article Title: Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
    Article Snippet: KCs and HaCaT cells were stimulated with a mix of proinflammatory cytokines namely IL-1α (Biomart), IL-6 (Peprotech), TNF-α (Prospec), IL-17 (Biomart), IL-22 (Peprotech) and IFN-γ (Peprotech), each at 50 ng/ml, for 24 h. Conditioned media were concentrated 10 times by using centrifugal concentrator with 10,000 MW cutoff (Vivaspin, Sartorius).

    Article Title: The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration
    Article Snippet: The concentration of IL-22 (PeproTech, cat: 200-22), IL-17A (PeproTech, cat: 200-17), TNF-α (PeproTech, cat: 300-01A), IL-1a (PeproTech, cat: 200-01A), and oncostatin M (PeproTech, cat: 300-10H) used in this study was 10 ng/mL.

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation.
    Article Snippet: The M6 cocktail contains IL-4 (10 ng/ml, Peprotech, Cat# 200--04), IL-17A (10 ng/ml, Peprotech, Cat# 200--17), IL-22 (10 ng/ml, Peprotech, Cat# 200--22), oncostatin M (10 ng/ml, Peprotech, Cat# 300--10), IL-1α (10 ng/ml, Peprotech, Cat# 200--01 A), and TNF-α (10 ng/ml, Peprotech, Cat# 300--01 A).

    Article Title: Platelet-Derived Soluble CD40L and Its Impact on Immune Modulation and Anti-IL6R Antibody Treatment Outcome in Rheumatoid Arthritis.
    Article Snippet: IFNγ, TNF (BD Biosciences), IL-17, VEGF, IL-22 (Peprotech), IL-6, sIL-6R, IL-10 (Immunotools), sCD62P (R&D, Minneapolis, MN, USA) PF-4, sCD40L, PDGF-BB (Peprotech), and latent TGFβ (Mabtech, Nacka Strand, Sweden) levels were determined using specific ELISA kits according to manufacturers’ instruction.

    Article Title: CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
    Article Snippet: Isolated LSECs were subsequently cultured on collagen-coated plates using IMDM medium (10% FBS) for 5 days before IL-22 (PeproTech) stimulation (50 ng/ml).

    Article Title: Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing
    Article Snippet: For the subsequent inflammatory model, additional cytokines including recombinant human interleukin (IL)-17A, tumor necrosis factor (TNF)-α and IL-22 (at a concentration of 50 ng/mL each) (catalog # 200-17, 300-01A, or 200-22, PeproTech, US) were added.

    Cell Culture:

    Article Title: C5a peptidase (ScpA) activity towards human type II and type III interferons.
    Article Snippet: IL-37, IL-22, IL-6, IL-8, IL10, IL-17A, IL-17E, IL-1α, IP-10, ENA-78, TNF-α, MIG, IFNβ, IFNω, IFNγ, IFNλ1, IFNλ2 were purchased from Peprotech.

    Article Title: Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis.
    Article Snippet: Circular RNA (circRNA) has been confirmed to participate in psoriasis process, but the role of circ_0024028 in psoriasis development is still unclear.. Interleukin 22 (IL-22)-induced keratinocytes (HaCaT) were used to construct psoriasis cell models in vitro.. The expression of circ_0024028, microRNA (miR)-486-3p and AKT serine/threonine kinase 3 (AKT3) was analyzed by quantitative real-time PCR.

    Article Title: Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
    Article Snippet: KCs and HaCaT cells were stimulated with a mix of proinflammatory cytokines namely IL-1α (Biomart), IL-6 (Peprotech), TNF-α (Prospec), IL-17 (Biomart), IL-22 (Peprotech) and IFN-γ (Peprotech), each at 50 ng/ml, for 24 h. Conditioned media were concentrated 10 times by using centrifugal concentrator with 10,000 MW cutoff (Vivaspin, Sartorius).

    Article Title: The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration
    Article Snippet: The concentration of IL-22 (PeproTech, cat: 200-22), IL-17A (PeproTech, cat: 200-17), TNF-α (PeproTech, cat: 300-01A), IL-1a (PeproTech, cat: 200-01A), and oncostatin M (PeproTech, cat: 300-10H) used in this study was 10 ng/mL.

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation.
    Article Snippet: The M6 cocktail contains IL-4 (10 ng/ml, Peprotech, Cat# 200--04), IL-17A (10 ng/ml, Peprotech, Cat# 200--17), IL-22 (10 ng/ml, Peprotech, Cat# 200--22), oncostatin M (10 ng/ml, Peprotech, Cat# 300--10), IL-1α (10 ng/ml, Peprotech, Cat# 200--01 A), and TNF-α (10 ng/ml, Peprotech, Cat# 300--01 A).

    Article Title: Platelet-Derived Soluble CD40L and Its Impact on Immune Modulation and Anti-IL6R Antibody Treatment Outcome in Rheumatoid Arthritis.
    Article Snippet: IFNγ, TNF (BD Biosciences), IL-17, VEGF, IL-22 (Peprotech), IL-6, sIL-6R, IL-10 (Immunotools), sCD62P (R&D, Minneapolis, MN, USA) PF-4, sCD40L, PDGF-BB (Peprotech), and latent TGFβ (Mabtech, Nacka Strand, Sweden) levels were determined using specific ELISA kits according to manufacturers’ instruction.

    Article Title: CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
    Article Snippet: Isolated LSECs were subsequently cultured on collagen-coated plates using IMDM medium (10% FBS) for 5 days before IL-22 (PeproTech) stimulation (50 ng/ml).

    Article Title: Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing
    Article Snippet: For the subsequent inflammatory model, additional cytokines including recombinant human interleukin (IL)-17A, tumor necrosis factor (TNF)-α and IL-22 (at a concentration of 50 ng/mL each) (catalog # 200-17, 300-01A, or 200-22, PeproTech, US) were added.

    Over Expression:

    Article Title: C5a peptidase (ScpA) activity towards human type II and type III interferons.
    Article Snippet: IL-37, IL-22, IL-6, IL-8, IL10, IL-17A, IL-17E, IL-1α, IP-10, ENA-78, TNF-α, MIG, IFNβ, IFNω, IFNγ, IFNλ1, IFNλ2 were purchased from Peprotech.

    Article Title: Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis.
    Article Snippet: Circular RNA (circRNA) has been confirmed to participate in psoriasis process, but the role of circ_0024028 in psoriasis development is still unclear.. Interleukin 22 (IL-22)-induced keratinocytes (HaCaT) were used to construct psoriasis cell models in vitro.. The expression of circ_0024028, microRNA (miR)-486-3p and AKT serine/threonine kinase 3 (AKT3) was analyzed by quantitative real-time PCR.

    Article Title: Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
    Article Snippet: KCs and HaCaT cells were stimulated with a mix of proinflammatory cytokines namely IL-1α (Biomart), IL-6 (Peprotech), TNF-α (Prospec), IL-17 (Biomart), IL-22 (Peprotech) and IFN-γ (Peprotech), each at 50 ng/ml, for 24 h. Conditioned media were concentrated 10 times by using centrifugal concentrator with 10,000 MW cutoff (Vivaspin, Sartorius).

    Article Title: The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration
    Article Snippet: The concentration of IL-22 (PeproTech, cat: 200-22), IL-17A (PeproTech, cat: 200-17), TNF-α (PeproTech, cat: 300-01A), IL-1a (PeproTech, cat: 200-01A), and oncostatin M (PeproTech, cat: 300-10H) used in this study was 10 ng/mL.

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation.
    Article Snippet: The M6 cocktail contains IL-4 (10 ng/ml, Peprotech, Cat# 200--04), IL-17A (10 ng/ml, Peprotech, Cat# 200--17), IL-22 (10 ng/ml, Peprotech, Cat# 200--22), oncostatin M (10 ng/ml, Peprotech, Cat# 300--10), IL-1α (10 ng/ml, Peprotech, Cat# 200--01 A), and TNF-α (10 ng/ml, Peprotech, Cat# 300--01 A).

    Article Title: Platelet-Derived Soluble CD40L and Its Impact on Immune Modulation and Anti-IL6R Antibody Treatment Outcome in Rheumatoid Arthritis.
    Article Snippet: IFNγ, TNF (BD Biosciences), IL-17, VEGF, IL-22 (Peprotech), IL-6, sIL-6R, IL-10 (Immunotools), sCD62P (R&D, Minneapolis, MN, USA) PF-4, sCD40L, PDGF-BB (Peprotech), and latent TGFβ (Mabtech, Nacka Strand, Sweden) levels were determined using specific ELISA kits according to manufacturers’ instruction.

    Article Title: CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
    Article Snippet: Isolated LSECs were subsequently cultured on collagen-coated plates using IMDM medium (10% FBS) for 5 days before IL-22 (PeproTech) stimulation (50 ng/ml).

    Article Title: Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing
    Article Snippet: For the subsequent inflammatory model, additional cytokines including recombinant human interleukin (IL)-17A, tumor necrosis factor (TNF)-α and IL-22 (at a concentration of 50 ng/mL each) (catalog # 200-17, 300-01A, or 200-22, PeproTech, US) were added.

    Transfection:

    Article Title: C5a peptidase (ScpA) activity towards human type II and type III interferons.
    Article Snippet: IL-37, IL-22, IL-6, IL-8, IL10, IL-17A, IL-17E, IL-1α, IP-10, ENA-78, TNF-α, MIG, IFNβ, IFNω, IFNγ, IFNλ1, IFNλ2 were purchased from Peprotech.

    Article Title: Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis.
    Article Snippet: Circular RNA (circRNA) has been confirmed to participate in psoriasis process, but the role of circ_0024028 in psoriasis development is still unclear.. Interleukin 22 (IL-22)-induced keratinocytes (HaCaT) were used to construct psoriasis cell models in vitro.. The expression of circ_0024028, microRNA (miR)-486-3p and AKT serine/threonine kinase 3 (AKT3) was analyzed by quantitative real-time PCR.

    Article Title: Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
    Article Snippet: KCs and HaCaT cells were stimulated with a mix of proinflammatory cytokines namely IL-1α (Biomart), IL-6 (Peprotech), TNF-α (Prospec), IL-17 (Biomart), IL-22 (Peprotech) and IFN-γ (Peprotech), each at 50 ng/ml, for 24 h. Conditioned media were concentrated 10 times by using centrifugal concentrator with 10,000 MW cutoff (Vivaspin, Sartorius).

    Article Title: The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration
    Article Snippet: The concentration of IL-22 (PeproTech, cat: 200-22), IL-17A (PeproTech, cat: 200-17), TNF-α (PeproTech, cat: 300-01A), IL-1a (PeproTech, cat: 200-01A), and oncostatin M (PeproTech, cat: 300-10H) used in this study was 10 ng/mL.

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation.
    Article Snippet: The M6 cocktail contains IL-4 (10 ng/ml, Peprotech, Cat# 200--04), IL-17A (10 ng/ml, Peprotech, Cat# 200--17), IL-22 (10 ng/ml, Peprotech, Cat# 200--22), oncostatin M (10 ng/ml, Peprotech, Cat# 300--10), IL-1α (10 ng/ml, Peprotech, Cat# 200--01 A), and TNF-α (10 ng/ml, Peprotech, Cat# 300--01 A).

    Article Title: Platelet-Derived Soluble CD40L and Its Impact on Immune Modulation and Anti-IL6R Antibody Treatment Outcome in Rheumatoid Arthritis.
    Article Snippet: IFNγ, TNF (BD Biosciences), IL-17, VEGF, IL-22 (Peprotech), IL-6, sIL-6R, IL-10 (Immunotools), sCD62P (R&D, Minneapolis, MN, USA) PF-4, sCD40L, PDGF-BB (Peprotech), and latent TGFβ (Mabtech, Nacka Strand, Sweden) levels were determined using specific ELISA kits according to manufacturers’ instruction.

    Article Title: CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
    Article Snippet: Isolated LSECs were subsequently cultured on collagen-coated plates using IMDM medium (10% FBS) for 5 days before IL-22 (PeproTech) stimulation (50 ng/ml).

    Article Title: Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing
    Article Snippet: For the subsequent inflammatory model, additional cytokines including recombinant human interleukin (IL)-17A, tumor necrosis factor (TNF)-α and IL-22 (at a concentration of 50 ng/mL each) (catalog # 200-17, 300-01A, or 200-22, PeproTech, US) were added.



    Similar Products

    96
    Miltenyi Biotec cytokines
    Analysis of <t>cytokines,</t> interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including <t>GM-CSF,</t> <t>MCP-1</t> and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).
    Cytokines, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/il-22+cytokine/IL-22+Antibody%2C+anti-human%2C+REAfinity/pmc12808506-367-4-39
    Average 96 stars, based on 1 article reviews
    cytokines - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    93
    R&D Systems il 22 cytokine concentrations
    Analysis of <t>cytokines,</t> interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including <t>GM-CSF,</t> <t>MCP-1</t> and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).
    Il 22 Cytokine Concentrations, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/il-22+cytokine/Human+IL-22+Quantikine+ELISA+Kit/pmc12284374-352-0-11
    Average 93 stars, based on 1 article reviews
    il 22 cytokine concentrations - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    90
    PeproTech il-22 cytokine
    Analysis of <t>cytokines,</t> interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including <t>GM-CSF,</t> <t>MCP-1</t> and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).
    Il 22 Cytokine, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/il-22+cytokine/il+22+cytokine/pm40358149-84-5-7
    Average 90 stars, based on 1 article reviews
    il-22 cytokine - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    96
    Miltenyi Biotec cytokine stimulation
    Analysis of <t>cytokines,</t> interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including <t>GM-CSF,</t> <t>MCP-1</t> and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).
    Cytokine Stimulation, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/il-22+cytokine/IL-22+Antibody%2C+anti-human%2C+REAfinity/pmc11914861__EJI___55___e202451437___s001-23-44-22
    Average 96 stars, based on 1 article reviews
    cytokine stimulation - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    90
    Speakman il-22 cytokine
    Analysis of <t>cytokines,</t> interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including <t>GM-CSF,</t> <t>MCP-1</t> and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).
    Il 22 Cytokine, supplied by Speakman, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/il-22+cytokine/il+22+cytokine/pm40055278-135-16-17
    Average 90 stars, based on 1 article reviews
    il-22 cytokine - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Beyotime bio-plex pro mouse cytokine il-22-plex assay kit
    Analysis of <t>cytokines,</t> interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including <t>GM-CSF,</t> <t>MCP-1</t> and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).
    Bio Plex Pro Mouse Cytokine Il 22 Plex Assay Kit, supplied by Beyotime, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/il-22+cytokine/il+22+cytokine/pm39954663-90-13-20
    Average 90 stars, based on 1 article reviews
    bio-plex pro mouse cytokine il-22-plex assay kit - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    Image Search Results


    Analysis of cytokines, interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including GM-CSF, MCP-1 and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).

    Journal: Redox Biology

    Article Title: Fenofibrate attenuates the adverse effects of radiation on endothelial cells through modulation of ROS-NO signalling and inflammation

    doi: 10.1016/j.redox.2025.103994

    Figure Lengend Snippet: Analysis of cytokines, interleukins and endothelial mesenchymal transition markers. qPCR analysis of inflammation markers 2d (A) and 7d (B), inflammatory regulators 2d (E) and 7d (F) and EndMT markers 2d (G) and 7d (H) were performed in irradiated HCAECs with and without fenofibrate (Feno). The release of different cytokines including GM-CSF, MCP-1 and IL-6 which were quantified using flow cytometry after 2d (C) and 7d (D). The error bars represent the standard deviation (±SD) (Two-way ANOVA, Tukey's multiple comparisons test; ∗ p ≤ 0.05; ∗∗ p ≤ 0.01; ∗∗∗p ≤ 0.001; ∗∗∗∗ p ≤ 0.0001; n = 3).

    Article Snippet: Extracellular release of inflammatory cytokines (e.g., M-CSF, Granzyme B, IFN-γ, IL-2, IL-4, IL-6, IL-10, IL-17A, IL-21, MCP-1 (CCL2), Perforin and TNF-α) in cell culture supernatants were quantitatively measured based on a fluorescent bead-based system using MACSPlex Cytokine Kits (#130-125-800; Miltenyi Biotec, Germany) according to the manufacturer's protocol.

    Techniques: Irradiation, Flow Cytometry, Standard Deviation

    Proposed mechanism of action of fenofibrate in irradiated HCAECs in-vitro . Irradiation reduced NO signalling via inactivation of the PI3K–AKT–eNOS pathway, whereas fenofibrate reactivated this pathway and restored NO production (A). Consistent with this, irradiation increased ROS generation, NOX activity, MDA levels, and 3-NT levels, while fenofibrate mitigated this effect (B). Irradiation also triggered an inflammatory response, which was counteracted by fenofibrate (C). The released cytokines contribute to inflammation, changes in cytoskeleton organisation and initiation of EndMT, and fenofibrate effectively attenuated the processes (D). Alterations in the pathways described above play a crucial role in the remodelling of vascular endothelial cells involved in the initiation and progression of atherosclerosis. Fenofibrate acts to reduce or restore the effects of irradiation on these pathways (E–F). Solid lines indicate correlations validated in this study, while dashed lines indicate unvalidated correlations.

    Journal: Redox Biology

    Article Title: Fenofibrate attenuates the adverse effects of radiation on endothelial cells through modulation of ROS-NO signalling and inflammation

    doi: 10.1016/j.redox.2025.103994

    Figure Lengend Snippet: Proposed mechanism of action of fenofibrate in irradiated HCAECs in-vitro . Irradiation reduced NO signalling via inactivation of the PI3K–AKT–eNOS pathway, whereas fenofibrate reactivated this pathway and restored NO production (A). Consistent with this, irradiation increased ROS generation, NOX activity, MDA levels, and 3-NT levels, while fenofibrate mitigated this effect (B). Irradiation also triggered an inflammatory response, which was counteracted by fenofibrate (C). The released cytokines contribute to inflammation, changes in cytoskeleton organisation and initiation of EndMT, and fenofibrate effectively attenuated the processes (D). Alterations in the pathways described above play a crucial role in the remodelling of vascular endothelial cells involved in the initiation and progression of atherosclerosis. Fenofibrate acts to reduce or restore the effects of irradiation on these pathways (E–F). Solid lines indicate correlations validated in this study, while dashed lines indicate unvalidated correlations.

    Article Snippet: Extracellular release of inflammatory cytokines (e.g., M-CSF, Granzyme B, IFN-γ, IL-2, IL-4, IL-6, IL-10, IL-17A, IL-21, MCP-1 (CCL2), Perforin and TNF-α) in cell culture supernatants were quantitatively measured based on a fluorescent bead-based system using MACSPlex Cytokine Kits (#130-125-800; Miltenyi Biotec, Germany) according to the manufacturer's protocol.

    Techniques: Irradiation, In Vitro, Activity Assay